Description

3,4-Diethoxy-n-Hydroxybenzamidine is a specialized amidine derivative, a high-purity chemical intermediate of significant interest in advanced organic synthesis. Its unique molecular structure, featuring both amidine and phenolic ether functionalities, makes it a valuable building block for constructing complex heterocyclic systems and pharmacologically active molecules. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and plant growth regulators, leveraging its amidine moiety for biological activity.
• Ligand and Chelating Agent Precursor: The amidine and hydroxy groups provide coordination sites, making it a useful starting material for synthesizing specialized ligands in catalysis and metal complexation.
• Fine Chemical Building Block: Employed in the multi-step synthesis of complex organic molecules, dyes, and functional polymers requiring specific amidine incorporation.
• Biochemical Research: Utilized in proteomics and enzyme inhibition studies as a potential scaffold for designing enzyme inhibitors or molecular probes.

Basic Information

Product Name	3,4-Diethoxy-n-Hydroxybenzamidine
CAS No.	1201448-00-1
Molecular Formula	C11H16N2O3
Molecular Weight	224.26 g/mol
Synonyms	3,4-Diethoxy-N-hydroxybenzamidine; 3,4-Diethoxybenzhydroxamic amidine; N-Hydroxy-3,4-diethoxybenzamidine; Benzamidine, N-hydroxy-3,4-diethoxy-; 1-(3,4-Diethoxyphenyl)-N-hydroxyformamidine; 3,4-Diethoxybenzohydroxamidine; 3,4-Diethoxybenzamidoxime (tautomeric form)
EINECS	Contact for details

Quality Control

Our 3,4-Diethoxy-n-Hydroxybenzamidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements of research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP and ISO standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.