Description

1H-Pyrazole, 1-(2-Methoxyethyl)-3,5-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, functionalized pyrazole boronic ester derivative, serving as a critical synthetic intermediate. Its core value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, scalable building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex heterocyclic cores.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific pyrazole motifs for bioactivity.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Suzuki-Miyaura Cross-Coupling: The protected boronic ester group makes it a stable and reactive partner for palladium-catalyzed carbon-carbon bond formation with aryl/heteroaryl halides.
• Chemical Biology & Proteomics: Can be utilized as a versatile handle for bioconjugation and the development of chemical probes.
• Ligand Synthesis: Acts as a starting material for the preparation of specialized ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	1H-Pyrazole, 1-(2-Methoxyethyl)-3,5-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	1200537-40-1
Molecular Formula	C₁₄H₂₅BN₂O₃
Molecular Weight	280.18 g/mol
Synonyms	1-(2-Methoxyethyl)-3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-methoxyethyl)-3,5-dimethylpyrazole; 1-(2-Methoxyethyl)-3,5-dimethyl-1H-pyrazole-4-boronic acid pinacol ester; 3,5-Dimethyl-1-(2-methoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole; Pyrazole-4-boronic acid pinacol ester derivative
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole boronic ester derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our production adheres to cGMP principles where applicable, ensuring reliable batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C (refrigerated) for long-term stability, although short-term storage at controlled room temperature (15-25°C) is acceptable. The container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.