Description

Ethyl 2-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is a high-value, synthetically versatile boronic ester derivative, serving as a critical building block in modern organic synthesis. Its primary commercial value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, scalable, and reliable intermediates for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for constructing biaryl and heterobiaryl scaffolds common in modern therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aromatic coupling reactions.
• Material Science & OLED Development: Acts as a monomer or building block for creating conjugated polymers and organic light-emitting diode (OLED) materials, where controlled molecular architecture is crucial.
• Ligand & Catalyst Preparation: Employed in the development of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic routes and creating complex organic molecules.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific aromatic substitutions.

Basic Information

Product Name	Ethyl 2-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate
CAS No.	1198615-87-0
Molecular Formula	C₁₈H₂₇BO₄
Molecular Weight	318.22 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methylbenzoic acid ethyl ester; Ethyl 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methylbenzoate; 2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid ethyl ester; 1198615-87-0; Benzoic acid, 2-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester; Ethyl 2-methyl-3-(pinacolatoboryl)benzoate; 3-Pinacolatoboryl-2-methylbenzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistent performance for sensitive cross-coupling reactions. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support compliance with relevant guidelines for use in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.