Description

Ethyl 3-(2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl)propanoate is a high-value organoboron building block, specifically a boronic ester derivative, essential for modern synthetic chemistry. This compound matters because it serves as a critical intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and conjugated systems. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional molecules. Its stability and reactivity profile make it a preferred reagent for constructing carbon-carbon bonds under mild conditions.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or substituted phenyl moieties.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science: Employed in the development of organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers where precise molecular architecture is crucial.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for methodology development and creating complex organic molecules via palladium-catalyzed cross-coupling.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other specialty chemicals requiring the introduction of a boronic ester functional group for further derivatization.

Basic Information

Product Name	Ethyl 3-(2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl)propanoate
CAS No.	1198615-84-7
Molecular Formula	C₁₉H₂₉BO₄
Molecular Weight	332.24 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzene propanoic acid ethyl ester; Ethyl 3-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propionate; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenethyl propionate; (2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoic acid ethyl ester; Ethyl 3-(2-(pinacolatoboryl)phenyl)propanoate; 1198615-84-7; Pinacol [2-(2-ethoxycarbonylethyl)phenyl]boronate
EINECS	Contact for details

Quality Control

Our Ethyl 3-(2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl)propanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR (¹H and ¹³C), and GC analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and cGMP intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.