Description

(3-Ethoxycarbonylmethylphenyl)Boronic Acid, Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical research for constructing complex biaryl structures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in creating complex biaryl and heterobiaryl scaffolds common in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific aromatic couplings.
• Material Science Research: Employed in the creation of organic electronic materials, such as those for OLEDs and organic photovoltaics, where precise molecular architecture is critical.
• Chemical Biology & Probe Development: Serves as a versatile reagent for labeling and modifying biomolecules or creating molecular probes for diagnostic applications.
• Catalyst & Ligand Preparation: Acts as a precursor for synthesizing specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis organizations (CSOs) and CDMOs producing bespoke organic compounds for client projects.

Basic Information

Product Name	(3-Ethoxycarbonylmethylphenyl)Boronic Acid, Pinacol Ester
CAS No.	1198615-70-1
Molecular Formula	C₁₆H₂₃BO₄
Molecular Weight	290.16 g/mol
Synonyms	[3-(Ethoxycarbonylmethyl)phenyl]boronic acid pinacol ester; 3-(Ethoxycarbonylmethyl)benzeneboronic acid pinacol ester; (3-Carbethoxymethylphenyl)boronic acid pinacol ester; Pinacol [3-(ethoxycarbonylmethyl)phenyl]boronate; B-[3-(Ethoxycarbonylmethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-(Ethoxycarbonylmethyl)phenylboronic acid pinacol ester; Boronic acid, B-[3-[(ethoxycarbonyl)methyl]phenyl]-, 1,1-dimethylethyl ester (9CI)
EINECS	Contact for details

Quality Control

Our (3-Ethoxycarbonylmethylphenyl)Boronic Acid, Pinacol Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive coupling reactions. Each lot undergoes comprehensive analytical characterization, including NMR, HPLC, and GC analysis, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent hydrolysis and maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.