Description

Methyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole-2-Carboxylate is a high-value boronic ester derivative that serves as a critical synthetic intermediate in modern organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to build novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of heterocyclic compounds with potential therapeutic activity.
• Agrochemical Synthesis: Used in the research and production of novel pesticides, herbicides, and fungicides by facilitating the introduction of the pyrrole-carboxylate moiety.
• Material Science Research: Serves as a precursor for organic electronic materials, such as conductive polymers and organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Employed in the creation of tagged molecules and bioconjugates for studying biological processes and drug discovery.
• Academic & R&D Laboratories: A versatile reagent for methodological development and the synthesis of complex natural product analogs and novel chemical entities.
• Scale-up Process Chemistry: Suitable for pilot plant and commercial-scale synthesis due to its stability as a protected boronic acid derivative.

Basic Information

Product Name	Methyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole-2-Carboxylate
CAS No.	1198605-53-6
Molecular Formula	C12H18BNO4
Molecular Weight	251.09 g/mol
Synonyms	Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-2-carboxylate; 1H-Pyrrole-2-carboxylic acid, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester; Methyl 4-(pinacolatoboryl)-1H-pyrrole-2-carboxylate; 4-Pinacolatoboryl-1H-pyrrole-2-carboxylic acid methyl ester; Methyl 4-borono-1H-pyrrole-2-carboxylate pinacol ester; CAS 1198605-53-6
EINECS	Contact for details

Quality Control

Our Methyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply chain integrity and documentation traceability meets the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C (refrigerated). Allow the container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.