Description

1-(2-Fluoroethyl)-1H-Pyrazole-3-Carboxylic Acid CAS NO 1198437-47-6 is a high-purity fluorinated pyrazole derivative, a critical building block in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which combines a reactive carboxylic acid group with a fluorine-substituted ethyl chain, enabling precise modifications for advanced material and pharmaceutical development. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Serves as a versatile building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs), leveraging the pyrazole core's coordinating properties.
• Material Science Research: Employed in the creation of advanced polymers and functional materials where the fluorine moiety imparts desirable characteristics like chemical resistance or altered surface energy.
• Chemical Biology Probes: Acts as a core structure for designing fluorescent tags, enzyme inhibitors, and other molecular probes used in biochemical and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse R&D projects.

Basic Information

Product Name	1-(2-Fluoroethyl)-1H-Pyrazole-3-Carboxylic Acid
CAS No.	1198437-47-6
Molecular Formula	C6H7FN2O2
Molecular Weight	158.13 g/mol
Synonyms	1-(2-Fluoroethyl)-1H-pyrazole-3-carboxylic acid; 3-Pyrazolecarboxylic acid, 1-(2-fluoroethyl)-1H-; 1H-Pyrazole-3-carboxylic acid, 1-(2-fluoroethyl)-; 1-(2-Fluoroethyl)-3-carboxypyrazole; 2-Fluoroethyl pyrazole-3-carboxylate; 1198437-47-6; FEPCA
EINECS	Contact for details

Quality Control

Our production of 1-(2-Fluoroethyl)-1H-Pyrazole-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.