Description

4,4,5,5-Tetramethyl-2-[12-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-8-Oxatricyclo-[7.4.0.07]Trid is a sophisticated, high-purity boronic ester derivative, a critical intermediate in modern synthetic chemistry. Its value lies in its role as a key building block for constructing complex molecular architectures, particularly in pharmaceutical research and advanced material science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for Suzuki-Miyaura cross-coupling reactions and other catalytic transformations.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for complex, polycyclic target molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific, sterically hindered boronic ester functionalities.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics, due to its stable boronate group.
• Suzuki-Miyaura Cross-Coupling: A premier reagent for forming carbon-carbon bonds in the presence of palladium catalysts, enabling the construction of biaryl and other conjugated systems.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-[12-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-8-Oxatricyclo-[7.4.0.07]Trid
CAS No.	1197989-83-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-8-oxatricyclo[7.4.0.0^{3,7}]trideca-1(9),3(7),4,10,12-pentaen-4,5,5,12-tetramethyl derivative; Pinacol boronate ester tricyclic derivative; Boronic acid, B-[4,5,5,12-tetramethyl-8-oxatricyclo[7.4.0.0^{3,7}]trideca-1(9),3(7),4,10,12-pentaen-2-yl]-, 1,1-dimethylethyl ester; Advanced Suzuki coupling reagent; Sterically hindered boronic ester; Tricyclic pinacol boronate.
EINECS	Contact for details

Quality Control

Every batch of our 4,4,5,5-Tetramethyl-2-[12-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-8-Oxatricyclo-[7.4.0.07]Trid is produced and tested under strict quality management systems. We employ advanced analytical techniques including NMR, HPLC, and GC to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and support your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, this material should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (NMR)	Conforms
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.