Description

1-(5-Bromo-2-Fluorophenyl)Butan-1-One is a high-purity, halogenated aromatic ketone building block essential for advanced organic synthesis. This compound is valued for its unique molecular architecture, which facilitates the introduction of both bromine and fluorine substituents into complex target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated phenyl ring.
• Material Science Chemistry: Serves as a monomer or functionalization agent in the synthesis of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for transition metal catalysis and organocatalysts.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Scale-Up: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) engaged in custom synthesis projects.

Basic Information

Product Name	1-(5-Bromo-2-Fluorophenyl)Butan-1-One
CAS No.	1197943-61-5
Molecular Formula	C10H10BrFO
Molecular Weight	245.09 g/mol
Synonyms	1-(5-Bromo-2-fluorophenyl)-1-butanone; 5'-Bromo-2'-fluorobutyrophenone; Butan-1-one, 1-(5-bromo-2-fluorophenyl)-; 5-Bromo-2-fluorobutyrophenone; 1-Butanone, 1-(5-bromo-2-fluorophenyl)-; 2-Fluoro-5-bromobutyrophenone; 1-(5-Bromo-2-fluoro-phenyl)-butan-1-one
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 1-(5-Bromo-2-Fluorophenyl)Butan-1-One is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity, purity, and the absence of critical impurities. We adhere to strict in-house specifications developed for research and process chemistry applications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.