Description

4-(Methylsulfonyl)-2-Piperazinobenzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperazine-benzoic acid core functionalized with a methylsulfonyl group. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly for central nervous system (CNS) and oncology applications. Our supply ensures consistent quality and reliable availability for your most demanding R&D and scale-up projects.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in neurological and oncological drug discovery.
• Chemical Biology Probe Synthesis: Used to create tool compounds for studying enzyme function and protein-protein interactions in biological pathways.
• Library Synthesis for High-Throughput Screening: Serves as a versatile scaffold for generating diverse compound libraries to identify new lead molecules.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale manufacturing of candidate drugs.
• Academic & Contract Research: Utilized in university and CRO settings for fundamental research in medicinal chemistry and pharmacology.

Basic Information

Product Name	4-(Methylsulfonyl)-2-Piperazinobenzoic Acid
CAS No.	1197193-32-0
Molecular Formula	C12H16N2O4S
Molecular Weight	284.33 g/mol
Synonyms	2-(Piperazin-1-yl)-4-(methylsulfonyl)benzoic Acid; 4-(Methylsulfonyl)-2-(1-piperazinyl)benzoic Acid; 4-Methanesulfonyl-2-piperazin-1-yl-benzoic Acid; Benzoic acid, 4-(methylsulfonyl)-2-(1-piperazinyl)-; 1197193-32-0; 4-Methylsulfonyl-2-piperazinobenzoic Acid
EINECS	Contact for details

Quality Control

Our 4-(Methylsulfonyl)-2-Piperazinobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.