Description

4-(4-Methylpiperazin-1-Yl)-2-(Methylsulfonyl)Benzaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzaldehyde core functionalized with methylpiperazine and methylsulfonyl groups. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drug candidates, particularly kinase inhibitors and receptor antagonists.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic targets.
• Organic Synthesis Building Block: Serves as a versatile aldehyde component in condensation and coupling reactions (e.g., reductive amination, Suzuki coupling) to create complex chemical libraries.
• Bioconjugation Reagent: The reactive aldehyde group can be utilized for labeling or linking biomolecules in probe development.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method validation in API manufacturing.

Basic Information

Product Name	4-(4-Methylpiperazin-1-Yl)-2-(Methylsulfonyl)Benzaldehyde
CAS No.	1197193-26-2
Molecular Formula	C13H18N2O3S
Molecular Weight	282.36 g/mol
Synonyms	2-(Methylsulfonyl)-4-(4-methyl-1-piperazinyl)benzaldehyde; 4-(4-Methylpiperazin-1-yl)-2-(methylsulfonyl)benzaldehyde; 2-Methanesulfonyl-4-(4-methylpiperazin-1-yl)benzaldehyde; Benzaldehyde, 4-(4-methyl-1-piperazinyl)-2-(methylsulfonyl)-; 1197193-26-2
EINECS	Contact for details

Quality Control

Our 4-(4-Methylpiperazin-1-Yl)-2-(Methylsulfonyl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.