Description

4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is a high-value, multi-functional boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via the versatile Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials development. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and organic electronics industries who require precise and reliable building blocks for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially in creating complex biaryl and heterobiaryl structures common in modern drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific phenolic and boronic ester functionalities.
• Material Science & Organic Electronics: A precursor for developing organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and other functional materials where its structure can be incorporated into conjugated polymers or small molecules.
• Ligand & Catalyst Development: Employed in the synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs) due to its phenolic and boronate ester groups.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic methodologies and creating compound libraries for screening.
• Fine Chemical Production: Serves as a specialized intermediate in the custom synthesis of complex, high-value fine chemicals and dyes.

Basic Information

Product Name	4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol
CAS No.	1196985-65-5
Molecular Formula	C₁₃H₁₉BO₃
Molecular Weight	234.10 g/mol
Synonyms	3-Hydroxy-4-methylphenylboronic acid pinacol ester; 2-(3-Hydroxy-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Methyl-3-(pinacolatoboryl)phenol; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methylphenol; Phenol, 4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 4-Methyl-3-boronoanisole pinacol ester (related form)
EINECS	Contact for details

Quality Control

Our 4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance for sensitive cross-coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.