Description

Chloro[2-(Dicyclohexylphosphino)-2'-(N,n-Dimethylamino)Biphenyl]Gold(I), 98% is a high-purity, air-stable gold(I) complex featuring a bulky, electron-rich JohnPhos-type ligand system. This compound matters as a highly effective and selective catalyst for a variety of organic transformations, particularly in the synthesis of complex pharmaceutical intermediates and fine chemicals. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-performance catalysts for cross-coupling and hydrofunctionalization reactions.

Application

• Catalyst for C-C and C-Heteroatom Bond Formation: Employed in gold-catalyzed cross-coupling reactions, such as Sonogashira and Suzuki-Miyaura type couplings, under mild conditions.
• Pharmaceutical Intermediate Synthesis: A key catalyst in the development and scale-up of active pharmaceutical ingredients (APIs), enabling efficient and selective synthetic routes.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, fragrances, and advanced organic compounds requiring precise catalytic control.
• Hydrofunctionalization Reactions: Catalyzes the addition of nucleophiles across unsaturated bonds (e.g., hydroamination, hydroalkoxylation) for building molecular complexity.
• Materials Science Research: Serves as a precursor or catalyst in the development of novel organic electronic materials and metal-organic frameworks (MOFs).
• Academic and Industrial R&D: A valuable tool for methodology development in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	Chloro[2-(Dicyclohexylphosphino)-2'-(N,n-Dimethylamino)Biphenyl]Gold(I), 98%
CAS No.	1196707-11-5
Molecular Formula	C32H42AuClNP
Molecular Weight	723.06 g/mol
Synonyms	Chloro[2-(dicyclohexylphosphino)-2'-(dimethylamino)biphenyl]gold(I); Chloro(2-(dicyclohexylphosphino)-2'-(dimethylamino)-1,1'-biphenyl)gold(I); Gold(I) Chloro(2-(dicyclohexylphosphino)-2'-(dimethylamino)biphenyl); Au(I)-JohnPhos Complex; (2-Biphenyl)di-tert-butylphosphine Gold(I) Chloride Analog; [AuCl(JohnPhos)]; Chloro(2-(dicyclohexylphosphino)-2'-(N,N-dimethylamino)biphenyl)gold
EINECS	Contact for details

Quality Control

Our Chloro[2-(Dicyclohexylphosphino)-2'-(N,n-Dimethylamino)Biphenyl]Gold(I), 98% is manufactured under strict quality protocols. Each batch undergoes rigorous analytical testing, including NMR (1H, 31P), HPLC, and elemental analysis, to ensure identity, purity, and consistency meet the highest standards for catalytic applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain long-term stability. The compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Gold (Au) Content	Contact for details
Solubility	Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.