Description

4-Phenoxy-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzaldehyde is a high-value, advanced pharmaceutical intermediate featuring a benzaldehyde core functionalized with a phenoxy group and a pinacol boronate ester. This compound matters as a versatile building block in modern synthetic chemistry, enabling key carbon-carbon bond-forming reactions like the Suzuki-Miyaura cross-coupling. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the synthesis of complex organic molecules and active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Suzuki-Miyaura Cross-Coupling: Serves as an organoboron reagent for palladium-catalyzed coupling with aryl/vinyl halides to construct biaryl and conjugated systems.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and functional materials.
• OLED and Electronic Material Research: Acts as a building block for organic semiconductors and light-emitting materials.
• Academic and Contract Research: Essential for methodological studies and custom synthesis projects in academic and CRO laboratories.

Basic Information

Product Name	4-Phenoxy-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzaldehyde
CAS No.	1196474-93-7
Molecular Formula	C19H21BO4
Molecular Weight	324.18 g/mol
Synonyms	2-Formyl-5-phenoxyphenylboronic acid pinacol ester; 4-Phenoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-phenoxybenzaldehyde; 5-Phenoxy-2-formylphenylboronic acid pinacol ester; (2-Formyl-5-phenoxyphenyl)boronic acid pinacol ester; 4-Phenoxy-2-(pinacolatoboryl)benzaldehyde
EINECS	Contact for details

Quality Control

Our 4-Phenoxy-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.