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2-(4-Cyclopentyloxy-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane CAS NO 1196396-29-8


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CAS No.:1196396-29-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(4-Cyclopentyloxy-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, process development, and specialty chemical synthesis.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing biphenyl or aryl-heteroaryl motifs.
  • Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aryl coupling steps.
  • Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
  • Ligand and Catalyst Development: Employed in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis.
  • Chemical Biology Probes: Utilized in the synthesis of tagged molecules and probes for studying biological pathways and target engagement.
  • Custom Synthesis and Contract Manufacturing: A reliable starting material for custom synthesis projects requiring precise, scalable cross-coupling reactions.

Basic Information

Product Name 2-(4-Cyclopentyloxy-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane
CAS No. 1196396-29-8
Molecular Formula C17H25BO3
Molecular Weight 288.19 g/mol
Synonyms 4-Cyclopentyloxyphenylboronic acid pinacol ester; 2-(4-Cyclopentyloxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (4-(Cyclopentyloxy)phenyl)boronic acid pinacol ester; 4-Cyclopentoxybenzeneboronic acid pinacol ester; Pinacol (4-cyclopentyloxyphenyl)boronate; B-(4-Cyclopentyloxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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Quality Control

Every batch of 2-(4-Cyclopentyloxy-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent in-house specifications designed to meet the demands of research and cGMP manufacturing environments. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and conformity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥97.0%
Purity (HPLC, Area%) ≥98.0%
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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