Description

2-Chloro-4-(Phenoxy)Phenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative, a critical intermediate in modern synthetic chemistry. Its primary value lies in enabling efficient and selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to build novel active ingredients and functional organic frameworks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for constructing biaryl and heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for diagnostic and research applications.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical and custom synthesis houses producing specialized compounds for clients.
• Academic & Industrial R&D: A standard reagent in laboratory-scale research for methodological development and exploring new chemical spaces.

Basic Information

Product Name	2-Chloro-4-(Phenoxy)Phenylboronic Acid Pinacol Ester
CAS No.	1196395-83-1
Molecular Formula	C18H20BClO3
Molecular Weight	330.61 g/mol
Synonyms	2-Chloro-4-phenoxyphenylboronic acid pinacol ester; [2-Chloro-4-(phenoxy)phenyl]boronic acid pinacol ester; 4-Chloro-4'-phenoxybiphenyl-2-ylboronic acid pinacol ester; 2-Chloro-4-phenoxybenzeneboronic acid pinacol ester; (2-Chloro-4-phenoxyphenyl)boronic acid pinacol ester; Pinacol [2-chloro-4-(phenoxy)phenyl]boronate; B-[2-Chloro-4-(phenoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(Phenoxy)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.