Description

2-(4-Bromo-3-Methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its core value lies in enabling efficient and selective carbon-carbon bond formation, specifically through the Suzuki-Miyaura cross-coupling reaction, which is fundamental to pharmaceutical and advanced materials research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and OLED materials industries who require reliable, high-quality intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing biaryl or substituted phenyl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific halogenated aromatic structures.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in organic light-emitting diodes (OLEDs) and semiconductors.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology & Probe Synthesis: Useful for labeling and modifying biomolecules or creating fluorescent probes and sensors for diagnostic applications.
• Academic & Contract Research: A staple reagent in university and CRO laboratories for methodological development and exploring new synthetic pathways.

Basic Information

Product Name	2-(4-Bromo-3-Methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS No.	1196394-83-8
Molecular Formula	C13H18BBrO3
Molecular Weight	313.00 g/mol
Synonyms	4-Bromo-3-methoxyphenylboronic acid pinacol ester; (4-Bromo-3-methoxyphenyl)boronic acid pinacol ester; Pinacol (4-bromo-3-methoxyphenyl)boronate; 2-(4-Bromo-3-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Bromo-3-methoxybenzeneboronic acid pinacol ester; B-(4-Bromo-3-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborinane; 1196394-83-8
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-3-Methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and lot-to-lot consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.