Description

Sulfathiazole-13C6 is a stable isotope-labeled analog of the classic sulfonamide antibiotic, Sulfathiazole, where six carbon atoms are replaced with the carbon-13 isotope. This compound is essential as an internal standard for precise quantitative analysis in mass spectrometry, ensuring accurate and reliable results in complex biological and pharmaceutical matrices. It is primarily required by analytical laboratories, contract research organizations (CROs), and pharmaceutical companies engaged in advanced pharmacokinetic studies, drug metabolism research, and quality control of antibiotic formulations.

Application

• Internal Standard for LC-MS/MS: Used as a critical reference compound in Liquid Chromatography-Tandem Mass Spectrometry for the quantification of Sulfathiazole in biological fluids (plasma, serum, urine) and tissue samples.
• Pharmacokinetic and Bioavailability Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Veterinary Drug Residue Analysis: Supports compliance testing for Sulfathiazole residues in food-producing animals to ensure food safety according to regulatory limits (e.g., EU MRLs).
• Pharmaceutical Quality Control: Serves as a high-purity standard for assay and impurity profiling of Sulfathiazole active pharmaceutical ingredients (APIs) and finished dosage forms.
• Environmental Monitoring: Facilitates the detection and quantification of sulfonamide antibiotic pollutants in water and soil samples.
• Metabolite Identification and Pathway Research: Aids in the structural elucidation of Sulfathiazole metabolites in in vitro and in vivo studies.

Basic Information

Product Name	Sulfathiazole-13C6
CAS No.	1196157-72-8
Molecular Formula	13C6H9N3O2S2
Molecular Weight	~263.29 (Exact weight available on COA)
Synonyms	4-Amino-N-(1,3-thiazol-2-yl)-13C6-benzenesulfonamide; [13C6]-Sulfathiazole; Sulfathiazole (13C6); 2-(p-Aminobenzenesulfonamido)thiazole-13C6; N1-(2-Thiazolyl)sulfanilamide-13C6; NSC-71948-13C6; Isotopically Labeled Sulfathiazole; Sulfathiazole Internal Standard
EINECS	Contact for details

Quality Control

Every batch of Sulfathiazole-13C6 is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data from NMR (1H, 13C), HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, isotopic enrichment, and solvent content to meet the stringent requirements of analytical and regulatory science.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be kept under inert atmosphere or desiccated upon opening for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0% (chemical purity)
Isotopic Enrichment	≥99 atom % 13C
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.