Description

4-Bromo-1,1-Difluorocyclohexane is a valuable fluorinated and halogenated cyclohexane derivative, serving as a versatile building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it a critical intermediate for introducing fluorinated cyclohexyl motifs into target molecules. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty materials sectors, where it is used to modulate the physical, chemical, and biological properties of novel compounds.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, particularly in medicinal chemistry programs targeting metabolic diseases and CNS disorders.
• Agrochemical Synthesis: Used in the creation of novel herbicides and pesticides, where the difluorocyclohexyl group can enhance bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal properties.
• Polymer & Resin Modification: Acts as a functional monomer or cross-linking agent to introduce fluorine into polymers, enhancing chemical resistance and surface properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic substitutions to construct complex, fluorinated molecular architectures.
• Fluorine-18 Radiochemistry Precursor: Potential use as a precursor for PET (Positron Emission Tomography) tracer development, given its bromine handle for isotopic labeling.

Basic Information

Product Name	4-Bromo-1,1-Difluorocyclohexane
CAS No.	1196156-51-0
Molecular Formula	C6H9BrF2
Molecular Weight	199.04 g/mol
Synonyms	1,1-Difluoro-4-bromocyclohexane; 4-Bromo-1,1-difluorocyclohexane; Cyclohexane, 4-bromo-1,1-difluoro-; 4-Bromocyclohexylidene difluoride
EINECS	Contact for details

Quality Control

Our 4-Bromo-1,1-Difluorocyclohexane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.