Description

Ethyl 5-Chloro-1,3,4-Oxadiazole-2-Carboxylate is a high-value heterocyclic building block and pharmaceutical intermediate. This compound is critical for the synthesis of novel active molecules, particularly in medicinal chemistry and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, crop protection, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting infectious diseases or metabolic disorders.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Research: Used in the development of advanced polymers and functional materials with specific electronic or photophysical properties.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Academic & Industrial R&D: Fundamental reagent for methodological development in organic synthesis and heterocyclic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules at various scales.

Basic Information

Product Name	Ethyl 5-Chloro-1,3,4-Oxadiazole-2-Carboxylate
CAS No.	1196154-19-4
Molecular Formula	C5H5ClN2O3
Molecular Weight	176.56 g/mol
Synonyms	5-Chloro-1,3,4-oxadiazole-2-carboxylic acid ethyl ester; Ethyl 5-chloro-1,3,4-oxadiazole-2-carboxylate; 2-Ethoxycarbonyl-5-chloro-1,3,4-oxadiazole; Ethyl 5-chlorooxadiazole-2-carboxylate; 5-Chloro-2-(ethoxycarbonyl)-1,3,4-oxadiazole; 1,3,4-Oxadiazole-2-carboxylic acid, 5-chloro-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Chloro-1,3,4-Oxadiazole-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.