Description

2-Aminopyridine-4-Boronic Acid Pinacol Ester is a high-value, multifunctional boronic ester derivative crucial for modern synthetic chemistry. This compound serves as a key protected boronic acid building block, enabling precise carbon-carbon and carbon-heteroatom bond formation via cross-coupling reactions. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A fundamental building block for constructing biaryl and heteroaryl structures in medicinal chemistry and material science.
• Pharmaceutical Intermediate: Synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing aminopyridine scaffolds.
• Agrochemical Research: Development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Ligand Synthesis: Preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Functional Material Development: Creation of organic electronic materials, sensors, and liquid crystals.
• Chemical Biology Probes: Used in the synthesis of molecular probes for studying biological systems and enzyme inhibition.

Basic Information

Product Name	2-Aminopyridine-4-Boronic Acid Pinacol Ester
CAS No.	1195995-72-2
Molecular Formula	C11H17BN2O2
Molecular Weight	220.08 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine; 2-Amino-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Amino-4-pyridineboronic acid pinacol ester; 4-(Pinacolatoboryl)pyridin-2-amine; 2-Amino-4-(pinacolboronato)pyridine; 2-Amino-4-boronopyridine pinacol ester; 2-AP-4-BPin
EINECS	Contact for details

Quality Control

Our 2-Aminopyridine-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.