Description

4-[3,5-Bis(Trifluoromethyl)Phenyl]Benzylamine Hcl CAS NO 1195901-45-1 is a high-value, fluorinated aromatic amine building block. This compound is critical for introducing the lipophilic and electron-withdrawing bis(trifluoromethyl)phenyl moiety into complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, where its unique properties can enhance metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitors and central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the trifluoromethyl groups contribute to improved lipophilicity and membrane penetration.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic electronic materials requiring fluorinated aromatic units.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	4-[3,5-Bis(Trifluoromethyl)Phenyl]Benzylamine Hydrochloride
CAS No.	1195901-45-1
Molecular Formula	C16H10ClF6N
Molecular Weight	389.70 g/mol
Synonyms	4-[3,5-Bis(trifluoromethyl)phenyl]benzylamine hydrochloride; 1-[4-(Aminomethyl)phenyl]-3,5-bis(trifluoromethyl)benzene hydrochloride; [4-[3,5-Bis(trifluoromethyl)phenyl]phenyl]methanamine hydrochloride; α-(4-Aminophenyl)-3,5-bis(trifluoromethyl)benzenemethanol hydrochloride (tautomer); 4-(3,5-Bis(trifluoromethyl)benzyl)aniline HCl; BTPB-HCl
EINECS	Contact for details

Quality Control

Our production of 4-[3,5-Bis(Trifluoromethyl)Phenyl]Benzylamine HCl adheres to stringent quality protocols suitable for advanced R&D and scale-up applications. Every batch is characterized and tested to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (HPLC), impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.