Description

1-Hydroxy-1,3-Dihydrobenzo[C][1,2]Oxaborole-6-Carbaldehyde is a specialized organic boron compound featuring a fused benzoxaborole core with an aldehyde functional group. This unique structure makes it a valuable high-purity building block for advanced research and synthesis, particularly in the development of novel pharmaceuticals and agrochemicals. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers working on boron-containing active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel boron-based drug candidates, particularly for protease inhibitors and anti-inflammatory agents.
• Agrochemical Research: Used in developing advanced fungicides and herbicides that leverage the unique bioactivity of the benzoxaborole moiety.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialty polymers with tailored properties.
• Chemical Synthesis: Acts as a versatile aldehyde-bearing synthon for constructing complex heterocyclic compounds via condensation and cyclization reactions.
• Bioconjugation: The aldehyde group enables site-specific labeling and conjugation of biomolecules for diagnostic and therapeutic applications.
• Catalyst Ligand Development: Investigated as a precursor for novel ligand systems in transition metal catalysis.

Basic Information

Product Name	1-Hydroxy-1,3-Dihydrobenzo[C][1,2]Oxaborole-6-Carbaldehyde
CAS No.	1195621-94-3
Molecular Formula	C8H7BO3
Molecular Weight	161.95 g/mol
Synonyms	6-Formyl-1-hydroxy-1,3-dihydro-2,1-benzoxaborole; 1-Hydroxy-1,3-dihydro-2,1-benzoxaborole-6-carboxaldehyde; 1,3-Dihydro-1-hydroxy-2,1-benzoxaborole-6-carbaldehyde; Benzoxaborole-6-carbaldehyde derivative; B-0663; (6-Formyl-1,3-dihydro-2,1-benzoxaborol-1-yl)oxidanyl
EINECS	Contact for details

Quality Control

Our 1-Hydroxy-1,3-Dihydrobenzo[C][1,2]Oxaborole-6-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and FTIR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its hygroscopic and easily oxidized nature, the container must be kept tightly sealed after each use to minimize exposure to moisture and air. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.