Description

(2,5-Difluorophenyl)(3-Nitrophenyl)Methanone is a specialized aromatic ketone building block featuring both difluoro and nitro substituents. This compound is valued for its role as a key intermediate in advanced organic synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the biological activity imparted by its fluorinated and nitro-functionalized structure.
• Material Science: Serves as a building block for synthesizing advanced polymers, liquid crystals, and organic electronic materials due to its rigid aromatic core and functional groups.
• Chemical Synthesis: Employed in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to create complex biaryl systems for further functionalization.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized dyes and pigments where the nitro group can be further reduced or transformed.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological studies and exploring new synthetic pathways.

Basic Information

Product Name	(2,5-Difluorophenyl)(3-Nitrophenyl)Methanone
CAS No.	1193512-72-9
Molecular Formula	C13H7F2NO3
Molecular Weight	263.20 g/mol
Synonyms	3'-Nitro-2',5'-difluorobenzophenone; 1-(2,5-Difluorophenyl)-3-nitrobenzen-1-one; (3-Nitrophenyl)(2,5-difluorophenyl)methanone; Methanone, (2,5-difluorophenyl)(3-nitrophenyl)-; 2',5'-Difluoro-3-nitrobenzophenone
EINECS	Contact for details

Quality Control

Our (2,5-Difluorophenyl)(3-Nitrophenyl)Methanone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.