Description

1-(4-Bromophenyl)Cyclobutanamine (Hydrochloride) is a high-purity, synthetically versatile organic building block primarily used in pharmaceutical research and development. This compound serves as a critical intermediate for constructing complex molecules, enabling the exploration of novel therapeutic agents. It is essential for medicinal chemists and R&D professionals in the pharmaceutical, agrochemical, and advanced material science industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Research: Intermediate in the development of new pesticides and herbicides, leveraging the bromophenyl and cyclobutyl motifs.
• Chemical Biology: Serves as a probe or ligand in the study of biological targets and enzyme inhibition.
• Material Science Precursor: Potential monomer or functional unit for advanced polymers and specialty materials.
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	1-(4-Bromophenyl)Cyclobutanamine (Hydrochloride)
CAS No.	1193389-40-0
Molecular Formula	C10H13BrN • HCl
Molecular Weight	262.58 g/mol (Free base: 226.12 g/mol)
Synonyms	1-(4-Bromophenyl)cyclobutan-1-amine hydrochloride; 4-Bromo-α-(cyclobutyl)benzenemethanamine hydrochloride; 1-(p-Bromophenyl)cyclobutanamine HCl; 1-Aminocyclobutyl-4-bromobenzene hydrochloride; (4-Bromophenyl)cyclobutanamine hydrochloride; 1-(4-Bromophenyl)cyclobutan-1-amine HCl; 4'-(Aminocyclobutyl)bromobenzene hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(4-Bromophenyl)Cyclobutanamine (Hydrochloride) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We adhere to cGMP principles where applicable, and each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Certificates are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.