Description

2,2,6,6-Tetrafluoromorpholine Hydrochloride (Wxfc0621S1) is a high-purity, organofluorine building block of significant interest in advanced synthetic chemistry. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where the introduction of fluorine atoms is critical for modulating biological activity, metabolic stability, and lipophilicity. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where fluorination enhances product efficacy and environmental profile.
• Fluorinated Ligand Synthesis: Serves as a precursor for creating specialized fluorinated ligands used in catalysis and material science.
• Advanced Material Development: Employed in the research of fluorinated polymers and liquid crystals with unique thermal and chemical resistance properties.
• Process Chemistry & Scale-up: Provides a reliable, high-quality building block for optimizing synthetic routes from laboratory to pilot plant and commercial production scales.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses serving the global life sciences market.

Basic Information

Item	Detail
Product Name	2,2,6,6-Tetrafluoromorpholine Hydrochloride (Wxfc0621S1)
CAS No.	1193388-15-6
Molecular Formula	C4H6ClF4NO
Molecular Weight	195.54 g/mol
Synonyms	2,2,6,6-Tetrafluoro-4-morpholinyl hydrochloride; 2,2,6,6-Tetrafluoromorpholine HCl; 4H-2,2,6,6-Tetrafluoromorpholine hydrochloride; Morpholine, 2,2,6,6-tetrafluoro-, hydrochloride; WXFC0621S1; Tetrafluoromorpholine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2,2,6,6-Tetrafluoromorpholine Hydrochloride is produced and tested under a strict quality management system. We guarantee high purity and batch-to-batch consistency through rigorous analytical protocols including NMR, HPLC, and Karl Fischer titration. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.