Description

6-(Cyclopentoxy)Pyridine-2-Boronic Acid Pinacol Ester is a high-value, organoboron building block designed for advanced synthetic chemistry. This compound matters as a key intermediate in cross-coupling reactions, enabling the precise construction of complex molecules for research and development. It is primarily needed by pharmaceutical, agrochemical, and advanced materials chemists for creating novel active ingredients and functional materials. Its stability as a pinacol ester makes it a reliable reagent for demanding synthetic routes.

Application

• Pharmaceutical Intermediate: A crucial building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing functionalized pyridine scaffolds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Employed in the synthesis of tagged molecules and bioconjugates for studying biological pathways and target engagement.
• Catalyst Ligand Development: Utilized to construct novel ligand systems for transition metal catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	6-(Cyclopentoxy)Pyridine-2-Boronic Acid Pinacol Ester
CAS No.	1193245-09-8
Molecular Formula	C16H24BNO3
Molecular Weight	289.18 g/mol
Synonyms	2-(6-Cyclopentoxypyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Cyclopentoxy-2-pyridineboronic acid pinacol ester; 6-Cyclopentoxypyridine-2-boronic acid pinacol ester; 2-(6-(Cyclopentyloxy)pyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Boronic acid, B-[6-(cyclopentyloxy)-2-pyridinyl]-, 1,1-dimethylethyl ester; 6-Cyclopentyloxypyridine-2-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 6-(Cyclopentoxy)Pyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.