Description

(R)-Boronva-(+)-Pinanediol-Hcl CAS NO 1193224-33-7 is a high-purity, chiral boronic ester derivative, specifically the hydrochloride salt of the pinanediol-protected variant. This compound matters as a critical chiral building block and ligand in asymmetric synthesis, enabling the precise construction of complex molecules with high enantiomeric purity. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for applications in cross-coupling reactions, catalysis, and the synthesis of active pharmaceutical ingredients (APIs).

Application

• As a chiral ligand or catalyst in asymmetric Suzuki-Miyaura and other transition-metal-catalyzed cross-coupling reactions.
• As a key chiral building block for the synthesis of enantiomerically pure pharmaceuticals and bioactive compounds.
• In the development and scale-up of novel synthetic routes for complex natural products and fine chemicals.
• For research in medicinal chemistry to create libraries of chiral molecules for biological screening.
• In the preparation of advanced materials where chiral induction at the molecular level is required.
• As a reagent in academic and industrial research focused on new methodologies in organoboron chemistry.

Basic Information

Product Name	(R)-Boronva-(+)-Pinanediol-Hcl
CAS No.	1193224-33-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(R)-(+)-Pinanediol Boronic Acid Ester Hydrochloride; (R)-Pinanediol Boronate HCl; (R)-Boronva Pinanediol Ester Hydrochloride; (1R,2R,3S,5R)-2,6,6-Trimethylbicyclo[3.1.1]heptane-2,3-diol (R)-Boronva Ester Hydrochloride; Chiral Pinanediol Boronate HCl Salt; (R)-Boronva Pinanediolato Hydrochloride; (R)-BPH-HCl
EINECS	Contact for details

Quality Control

Our (R)-Boronva-(+)-Pinanediol-Hcl is manufactured under strict quality control protocols to ensure high chemical purity and chiral integrity, suitable for demanding synthetic applications. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and chiral analysis. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) and store the container in a desiccator to minimize exposure to moisture. Long-term storage at 2-8°C is advised for optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.