Description

1-(2-Iodo-4-Trifluoromethyl-Phenyl)-Ethanone is a high-purity, advanced pharmaceutical intermediate featuring a unique trifluoromethyl and iodo-substituted aromatic ketone structure. This compound is critical for the synthesis of complex molecules, where its halogenated and fluorinated groups serve as key handles for further functionalization and to modulate biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, where the trifluoromethyl group often enhances lipophilicity and metabolic stability.
• Ligand & Catalyst Precursor: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in cross-coupling reactions (e.g., Suzuki, Heck).
• Material Science: Employed in the research and development of advanced organic electronic materials, such as OLEDs and semiconductors, due to its electron-withdrawing substituents.
• Fluorine Chemistry Studies: An important reagent for academic and industrial research focused on introducing fluorine and iodine atoms into complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	1-(2-Iodo-4-Trifluoromethyl-Phenyl)-Ethanone
CAS No.	1192931-76-2
Molecular Formula	C9H6F3IO
Molecular Weight	314.05 g/mol
Synonyms	2'-Iodo-4'-(trifluoromethyl)acetophenone; 1-[2-Iodo-4-(trifluoromethyl)phenyl]ethanone; 2-Iodo-4-trifluoromethylacetophenone; α,α,α-Trifluoro-2-iodo-4-acetyltoluene; 2-Iodo-α,α,α-trifluoro-p-acetyltoluene; 4-Acetyl-3-iodobenzotrifluoride; Ethanone, 1-[2-iodo-4-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 1-(2-Iodo-4-Trifluoromethyl-Phenyl)-Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.