Description

[((Sa,S))-Dtb-Ph-Siphox)Ir(Cod)]Barf CAS NO 1192772-66-9 is a highly specialized, chiral iridium-based organometallic catalyst, specifically an iridium(I) complex bearing a phosphine-oxazoline (SIPHOS-type) ligand and a BArF counterion. This compound is engineered for exceptional enantioselectivity and reactivity in asymmetric hydrogenation and other transition metal-catalyzed transformations. It is a critical reagent for research and development chemists in the pharmaceutical and fine chemical industries, where precise stereochemical control is paramount for synthesizing chiral intermediates and active pharmaceutical ingredients (APIs).

Application

• Asymmetric Hydrogenation Catalyst: Primary application for the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Key catalyst in the production of chiral building blocks for high-value APIs, including those for cardiovascular, neurological, and oncological treatments.
• Fine Chemical Manufacturing: Enables the synthesis of enantiomerically pure flavors, fragrances, and agrochemical intermediates.
• Methodology Development: Used in academic and industrial R&D for developing new catalytic asymmetric reactions and optimizing existing processes.
• Chiral Ligand Screening: Serves as a pre-formed catalyst complex for evaluating and comparing the performance of chiral phosphine-oxazoline ligand frameworks.

Basic Information

Item	Detail
Product Name	[((Sa,S))-Dtb-Ph-Siphox)Ir(Cod)]Barf
CAS No.	1192772-66-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Iridium(1+), (1,2,5,6-η)-1,5-cyclooctadiene-[(2S)-4,5-dihydro-2-[5-(2,4,6-triisopropylphenyl)-2-thienyl]-4-(1,1-dimethylethyl)-4,5-dihydro-5-methyloxazole-κN3,κC2]-, (SP-4-2)-, tetrakis[3,5-bis(trifluoromethyl)phenyl]borate(1-); (S)-DTB-SIPHOS-Ir(cod) BArF; (S)-DTB-SIPHOS iridium(I) BArF complex; Chiral Iridium(I) SIPHOS Catalyst; Iridium(I)-(S)-DTB-SIPHOS BArF Salt
EINECS	Contact for details

Quality Control

Every batch of our [((Sa,S))-Dtb-Ph-Siphox)Ir(Cod)]Barf is synthesized and handled under inert atmosphere to preserve its catalytic activity. The product undergoes rigorous analytical characterization, including NMR spectroscopy and elemental analysis, to confirm identity, enantiomeric purity, and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or production protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C or as specified on the label or COA. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light will degrade its catalytic performance.

Specification

Item	Specification
Appearance	Orange to red crystalline or amorphous solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Area %)
Enantiomeric Purity	≥99% ee
Solubility	Soluble in dichloromethane, toluene, THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.