Description

4-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)Phenol is a high-purity boronic ester derivative of phenol, serving as a crucial synthetic intermediate in modern organic chemistry. Its primary value lies in its stability and reactivity, making it an essential building block for constructing complex molecules via cross-coupling reactions. This compound is particularly vital for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality precursors for Suzuki-Miyaura and other palladium-catalyzed couplings.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing biaryl or phenolic motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific phenolic-boronate structures.
• Material Science & OLED Development: Serves as a precursor for creating organic electronic materials, including ligands for metal-organic frameworks (MOFs) and emissive layers in organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Employed in the synthesis of specialty polymers and functionalized resins where phenolic boronic esters act as monomers or cross-linking agents.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes and sensors that leverage boronate chemistry for detecting biological analytes.
• Academic & Industrial R&D: A fundamental reagent for methodological development in cross-coupling chemistry and the exploration of new synthetic pathways.

Basic Information

Product Name	4-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)Phenol
CAS No.	1192765-29-9
Molecular Formula	C11H15BO3
Molecular Weight	206.05 g/mol
Synonyms	4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)phenol; 2-(4-Hydroxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)benzenol; Phenol, 4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-; 4-Hydroxyphenylboronic acid, pinacol ester; 4-Pinacolatoborylphenol; 4-Boronophenol pinacol ester
EINECS	Contact for details

Quality Control

Our 4-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.