Description

Ethyl 4-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)Benzoate is a high-purity boronic ester derivative, serving as a crucial synthetic intermediate in modern organic and medicinal chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or aryl-heteroaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aryl coupling steps.
• Material Science: Serves as a precursor for organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and bioconjugation reagents due to its reactive boronate functionality.
• Academic & Contract Research: A valuable reagent for methodology development and complex molecule synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Ethyl 4-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)Benzoate
CAS No.	1192765-24-4
Molecular Formula	C15H21BO4
Molecular Weight	276.14 g/mol
Synonyms	4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)benzoic acid ethyl ester; Ethyl 4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzoate; 4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)benzoic acid ethyl ester; 2-(4-Ethoxycarbonylphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; Benzoic acid, 4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-, ethyl ester; Ethyl p-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzoate
EINECS	Contact for details

Quality Control

Our Ethyl 4-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged manipulations to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.