Description

7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzo[B]Furan is a high-purity, advanced pharmaceutical intermediate featuring a benzo[b]furan core functionalized with a pinacol boronate ester group. This compound is a critical building block in modern synthetic chemistry, enabling efficient cross-coupling reactions for the construction of complex molecular architectures. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and materials science sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the discovery and development of new active ingredients for crop protection and pest management.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport or emissive layer materials in advanced display and lighting technologies.
• Material Science: Employed in the synthesis of conjugated polymers and organic semiconductors for electronic applications.
• Chemical Biology: Utilized as a probe or linker in bioconjugation and the development of chemical tools for biological study.
• Academic & Contract Research: Essential for methodological development and synthetic route exploration in university and CRO laboratories.

Basic Information

Item	Detail
Product Name	7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzo[B]Furan
CAS No.	1192755-14-8
Molecular Formula	C₁₆H₂₁BO₃
Molecular Weight	272.15 g/mol
Synonyms	7-Benzo[b]furanboronic acid pinacol ester; 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzofuran; Benzo[b]furan-7-boronic acid pinacol ester; 7-Pinacolatoborylbenzo[b]furan; 7-(Pinacolatoboryl)benzo[b]furan; 7-Boronobenzo[b]furan pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzo[B]Furan is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to moisture. Recommended storage temperature: 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.