Description

2-(5-Bromo-2-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling reactions.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis and R&D: A versatile reagent for contract research organizations (CROs) and academic laboratories engaged in novel organic compound development.

Basic Information

Product Name	2-(5-Bromo-2-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1192051-39-0
Molecular Formula	C13H18BBrO2
Molecular Weight	297.00 g/mol
Synonyms	5-Bromo-2-methylbenzeneboronic acid pinacol ester; (5-Bromo-2-methylphenyl)boronic acid pinacol ester; 2-Methyl-5-bromophenylboronic acid pinacol ester; Pinacol (5-bromo-2-methylphenyl)boronate; 5-Bromo-2-methylphenyl-Bpin; B-(5-Bromo-2-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(5-Bromo-2-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, ¹¹B), HPLC, and GC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with lot-specific data are provided to guarantee consistency and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.