Description

1-(2-Fluoro-3-Hydroxyphenyl)Ethanone is a fluorinated aromatic ketone derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a ketone and a phenolic hydroxyl group adjacent to a fluorine atom, makes it a critical building block for constructing complex molecules with tailored properties. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries who require precise, high-purity intermediates for synthesizing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in developing kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used as a building block for creating advanced herbicides, fungicides, and pesticides with enhanced efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Serves as a fluorinated core structure in the development of electronic materials for displays and lighting applications.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to impart specific thermal, optical, or solubility properties to high-performance polymers.
• Chemical Research & Development: A valuable reagent for method development and exploring new fluorination chemistry and cross-coupling reactions in academic and industrial R&D labs.
• Dye & Pigment Industry: Intermediate for synthesizing specialized fluorinated dyes and pigments with improved lightfastness and color properties.

Basic Information

Product Name	1-(2-Fluoro-3-Hydroxyphenyl)Ethanone
CAS No.	1191999-09-3
Molecular Formula	C8H7FO2
Molecular Weight	154.14 g/mol
Synonyms	2'-Fluoro-3'-hydroxyacetophenone; 1-(2-Fluoro-3-hydroxyphenyl)ethan-1-one; 3-Acetyl-2-fluorophenol; 2-Fluoro-3-hydroxyacetophenone; 2-Fluoro-3-acetylphenol; 1-Acetyl-2-fluoro-3-hydroxybenzene; 2-Fluoro-3-(1-oxoethyl)phenol
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-3-Hydroxyphenyl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.