Description

n-Cyclobutylidene-2-Methylpropane-2-Sulfinamide is a specialized chiral sulfinamide building block used in asymmetric synthesis. This compound matters for its role as a high-purity intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce stereochemical complexity into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral auxiliary or precursor in the asymmetric synthesis of complex drug candidates, particularly for introducing nitrogen-containing stereocenters.
• Agrochemical Synthesis: Used in the research and production of advanced, enantiomerically pure pesticides and herbicides.
• Ligand and Catalyst Development: Serves as a starting material for the synthesis of novel chiral ligands and organocatalysts used in stereoselective transformations.
• Academic and Industrial R&D: Employed in methodological research for new C-N bond-forming reactions and the construction of nitrogen heterocycles.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value, optically active specialty chemicals and flavors/fragrances intermediates.

Basic Information

Product Name	n-Cyclobutylidene-2-Methylpropane-2-Sulfinamide
CAS No.	1191456-53-7
Molecular Formula	C8H15NOS
Molecular Weight	173.28 g/mol
Synonyms	N-Cyclobutylidene-2-methylpropane-2-sulfinamide; 2-Methyl-N-(cyclobutylidene)propane-2-sulfinamide; tert-Butanesulfinamide, N-cyclobutylidene-; (E/Z)-N-Cyclobutylidene-2-methylpropane-2-sulfinamide; Cyclobutanone tert-Butanesulfinyl Imine; Cyclobutanone tert-Butylsulfinyl Imine; tert-Butylsulfinyl Cyclobutanone Imine; Sulfinamide Chiral Building Block CAS 1191456-53-7
EINECS	Contact for details

Quality Control

Our n-Cyclobutylidene-2-Methylpropane-2-Sulfinamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting research and process development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.