Description

1-(4-Fluorobenzoyl)Cyclopropanecarboxylic Acid is a high-purity fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the cyclopropane and fluorinated aryl motifs are crucial for modulating biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate these privileged structural elements into new molecular entities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances lipophilicity and target binding.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential intermediate for synthesizing specialty polymers or liquid crystals with unique optical or electronic properties.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and custom synthesis facilities for client-directed projects.
• Academic Research: Used in university and institutional labs for methodological studies in organic synthesis and fluorine chemistry.

Basic Information

Product Name	1-(4-Fluorobenzoyl)Cyclopropanecarboxylic Acid
CAS No.	1191284-11-3
Molecular Formula	C11H9FO3
Molecular Weight	208.19 g/mol
Synonyms	1-(4-Fluorobenzoyl)cyclopropanecarboxylic acid; Cyclopropanecarboxylic acid, 1-(4-fluorobenzoyl)-; 4-Fluorophenyl cyclopropanecarbonyl ketone carboxylic acid; 1-(p-Fluorobenzoyl)cyclopropanecarboxylic acid; 1-(4-Fluorobenzoyl)cyclopropane-1-carboxylic acid; 1-(4-Fluorophenyl)(oxo)methyl]cyclopropane-1-carboxylic acid; 1191284-11-3; FC-BZA-01 (Potential internal/research code)
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorobenzoyl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with complete chromatographic and spectroscopic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect this light-sensitive and moisture-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.