Description

Carbamic Acid, n-Methyl-n-[2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Ethyl]-, 1,1-Dimethylethyl Ester is a high-value, advanced pharmaceutical intermediate featuring a protected carbamate group and a pinacol boronate ester moiety. This compound is essential for modern synthetic chemistry, particularly in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex carbon-carbon bonds. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those requiring aryl-aryl bond formation via palladium-catalyzed cross-coupling.
• Agrochemical Research: Used in the development of new pesticides and herbicides where the boronate ester group facilitates the introduction of aromatic segments.
• Material Science: Serves as a precursor for creating organic electronic materials, such as polymers for OLEDs or organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents due to its reactive handle.
• Academic & Industrial R&D: A versatile reagent for methodology development and exploring new synthetic pathways in organic chemistry laboratories.
• Ligand Synthesis: Can be used to construct sophisticated ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	Carbamic Acid, n-Methyl-n-[2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Ethyl]-, 1,1-Dimethylethyl Ester
CAS No.	1191063-31-6
Molecular Formula	C20H32BNO4
Molecular Weight	361.29 g/mol
Synonyms	tert-Butyl N-methyl-N-[2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethyl]carbamate; N-Boc-N-methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethan-1-amine; 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-N-(tert-butoxycarbonyl)-N-methylethanamine; 1191063-31-6; BOC-N-Me-2-(4-Bpin-phenyl)ethylamine; (2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)(methyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, n-Methyl-n-[2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Ethyl]-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization using techniques including NMR (1H, 13C, 11B), HPLC, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.