Description

(Z)-4-(3-((5-(4-Bromophenyl)Furan-2-Yl)Methylene)-2-Oxo-5-Phenyl-2,3-Dihydro-1H-Pyrrol-1-Yl)Benzoic Acid is a high-purity, non-racemic organic compound featuring a complex molecular architecture that serves as a critical advanced pharmaceutical intermediate and research chemical. Its value lies in its precise stereochemistry and functional groups, making it an essential building block for the synthesis of novel bioactive molecules. This product is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in oncology and targeted drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the multi-step synthesis of potential drug candidates, especially kinase inhibitors and other targeted small-molecule therapies.
• Medicinal Chemistry Research: Used as a core scaffold or a derivatization starting point for structure-activity relationship (SAR) studies and high-throughput screening libraries.
• Organic Synthesis Building Block: Employed in complex organic transformations, including cross-coupling reactions and cyclizations, due to its bromophenyl and benzoic acid functionalities.
• Biochemical Probe Development: Serves as a ligand or inhibitor in biochemical assays to study specific protein targets and biological pathways.
• Material Science Research: Investigated for its potential use in creating organic electronic materials or nonlinear optical (NLO) materials due to its extended π-conjugated system.

Basic Information

Product Name	(Z)-4-(3-((5-(4-Bromophenyl)Furan-2-Yl)Methylene)-2-Oxo-5-Phenyl-2,3-Dihydro-1H-Pyrrol-1-Yl)Benzoic Acid
CAS No.	1191052-37-5
Molecular Formula	C28H18BrNO4
Molecular Weight	512.35 g/mol
Synonyms	(Z)-4-[3-[(5-(4-Bromophenyl)-2-furanyl)methylene]-2-oxo-5-phenyl-1-pyrrolyl]benzoic acid; 4-[3-[(5-(4-Bromophenyl)furan-2-yl)methylidene]-2-oxo-5-phenyl-3H-pyrrol-1-yl]benzoic acid; (Z)-4-(3-((5-(4-Bromophenyl)furan-2-yl)methylene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoic acid; Benzoic acid, 4-[3-[(5-(4-bromophenyl)-2-furanyl)methylene]-2-oxo-5-phenyl-1-pyrrolyl]-, (Z)-; CAS 1191052-37-5
EINECS	Contact for details

Quality Control

Our production of (Z)-4-(3-((5-(4-Bromophenyl)Furan-2-Yl)Methylene)-2-Oxo-5-Phenyl-2,3-Dihydro-1H-Pyrrol-1-Yl)Benzoic Acid adheres to stringent cGMP and ISO 9001 quality management principles. Every batch undergoes comprehensive analytical characterization, including HPLC for purity and chiral integrity, NMR for structural confirmation, and MS for identity verification. A detailed Certificate of Analysis (COA) documenting all specifications is provided with each shipment to ensure full traceability and compliance with your research or manufacturing protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is stable under inert atmosphere but may degrade upon prolonged exposure to strong acids or certain organic solvents. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0% (Area %)
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Z-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.