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2,6-Dichloro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzaldehyde CAS NO 1190989-28-6
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CAS No.:1190989-28-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2,6-Dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-benzaldehyde is a high-value, multi-functional boronic ester derivative that serves as a critical synthetic intermediate. Its primary commercial value lies in enabling efficient cross-coupling reactions, most notably the Suzuki-Miyaura reaction, which is fundamental to modern pharmaceutical and advanced materials research. This compound is essential for researchers and process chemists in pharmaceutical development, agrochemical synthesis, and the creation of organic electronic materials.
Application
- Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
- Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require complex, halogenated aromatic structures.
- Material Science: Serves as a precursor for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced organic electronic materials.
- Chemical Research & Development: A versatile reagent for constructing complex, functionalized biaryl and heterobiaryl scaffolds in medicinal and synthetic chemistry.
- Ligand & Catalyst Development: Employed in the synthesis of novel bidentate ligands and organometallic catalysts.
- Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise, site-specific functionalization of aromatic rings.
Basic Information
| Item | Details |
|---|---|
| Product Name | 2,6-Dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-benzaldehyde |
| CAS No. | 1190989-28-6 |
| Molecular Formula | C13H15BCl2O3 |
| Molecular Weight | 301.38 g/mol |
| Synonyms | 2,6-Dichloro-4-formylphenylboronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-dichlorobenzaldehyde; 2,6-Dichloro-4-(pinacolatoboron)benzaldehyde; (2,6-Dichloro-4-formylphenyl)boronic acid pinacol ester; Benzaldehyde, 2,6-dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2,6-Dichloro-4-borono-benzaldehyde pinacol ester |
| EINECS | Contact for details |
Quality Control
Every batch of 2,6-Dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-benzaldehyde is produced and tested under a strict quality management system to ensure high purity, consistency, and reliability for sensitive synthetic applications. Our products undergo rigorous quality testing, including HPLC, NMR, and GC analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity and impurity profiles are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity and reactivity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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