Description

Methyl 3-Borono-2,6-Difluorobenzoate is a high-purity, multifunctional organic building block containing both a boronic acid pinacol ester moiety and a methyl ester group. This compound is of significant value in modern synthetic chemistry, particularly for its role in facilitating key carbon-carbon bond-forming reactions. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients. Its specific structure makes it a critical intermediate in the synthesis of complex molecules via cross-coupling methodologies.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for constructing biaryl systems found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides requiring specific fluorinated and boronate-substituted aromatic cores.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials, ligands for catalysts, and specialty polymers.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and tags for studying biological processes due to its reactive handles.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Details
Product Name	Methyl 3-Borono-2,6-Difluorobenzoate
CAS No.	1190989-12-8
Molecular Formula	C9H9BF2O4
Molecular Weight	229.98 g/mol
Synonyms	Methyl 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-difluorobenzoate; 2,6-Difluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid Methyl Ester; 3-Borono-2,6-difluorobenzoic Acid Methyl Ester, Pinacol Ester; 1190989-12-8; Methyl 2,6-Difluoro-3-(pinacolatoboryl)benzoate
EINECS	Contact for details

Quality Control

Our Methyl 3-Borono-2,6-Difluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.