Description

Potassium 2-Chlorothiophene-5-Trifluoroborate is a high-value organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its primary value lies in its exceptional stability and reactivity, making it a superior alternative to traditional boronic acids in cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to construct complex molecular architectures with high precision and efficiency.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific thiophene-based structures.
• Material Science: Serves as a precursor for creating functionalized polymers, organic semiconductors, and liquid crystal materials.
• Chemical Research: An indispensable tool in academic and industrial R&D for exploring new C-C bond formation methodologies and constructing complex heterocyclic compounds.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts.

Basic Information

Product Name	Potassium 2-Chlorothiophene-5-Trifluoroborate
CAS No.	1190883-05-6
Molecular Formula	C4H2BClF3KS
Molecular Weight	218.48 g/mol
Synonyms	Potassium (2-Chlorothiophen-5-yl)trifluoroborate; 2-Chloro-5-trifluoroboratothiophene Potassium Salt; 2-Chlorothiophene-5-boronic Acid Trifluoroborate Potassium Salt; Potassium 2-Chloro-5-thienyltrifluoroborate; 2-Chloro-5-thienyltrifluoroborate Potassium Salt; 5-(Trifluoroborato)-2-chlorothiophene Potassium Salt; (2-Chloro-5-thienyl)potassium trifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium 2-Chlorothiophene-5-Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, ¹¹B, ¹⁹F), HPLC for purity, and KF titration for moisture content, to ensure it meets the high standards required for sensitive cross-coupling applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to prevent degradation. Keep away from incompatible materials such as strong acids and strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
¹¹B NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMF, DMSO; partially soluble in water, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.