Description

(2-Chloro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol is a high-value boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides through targeted molecular construction.
• Material Science: Precursor for organic electronic materials, including OLEDs, organic photovoltaics, and conductive polymers.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the synthesis of molecular probes and imaging agents.
• Academic & Contract Research: Enables exploratory research in synthetic methodology and the discovery of new chemical entities.
• Custom Synthesis: A critical starting material for contract manufacturing organizations (CMOs) producing bespoke fine chemicals.

Basic Information

Product Name	(2-Chloro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol
CAS No.	1190875-60-5
Molecular Formula	C13H18BClO3
Molecular Weight	268.54 g/mol
Synonyms	2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl alcohol; (2-Chloro-4-(pinacolatoboranyl)phenyl)methanol; 4-(Pinacolatoboran-2-yl)-2-chlorobenzyl alcohol; 2-Chloro-4-(pinacolboron)benzyl alcohol; 2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenemethanol; 2-Chloro-4-(pinacolatoboran-2-yl)benzyl alcohol; 2-Chloro-4-(pinacolato)boronbenzyl alcohol; 4-(Pinacolatoboran-2-yl)-2-chlorobenzenemethanol
EINECS	Contact for details

Quality Control

Our (2-Chloro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and production needs with material that meets the stringent standards required for pharmaceutical R&D and commercial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and moisture-sensitive nature. Allow the container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.