Description

1-(3,5-Dichloro-4-Fluorophenyl)-2,2,2-Trifluoroethanone is a high-value fluorinated aromatic ketone building block, essential for synthesizing advanced chemical intermediates. Its unique trifluoroacetyl and halogenated phenyl structure makes it a critical precursor for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for creating compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-infective agents.
• Agrochemical Synthesis: Serves as a crucial building block for creating next-generation herbicides and fungicides with improved efficacy and environmental profiles.
• Material Science Research: Used in the synthesis of specialty polymers and liquid crystals where fluorinated aromatic units impart desirable thermal and chemical resistance.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions and as a substrate for developing new fluorination methodologies in academic and industrial R&D.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	1-(3,5-Dichloro-4-Fluorophenyl)-2,2,2-Trifluoroethanone
CAS No.	1190865-44-1
Molecular Formula	C8H2Cl2F4O
Molecular Weight	260.99 g/mol
Synonyms	3,5-Dichloro-4-fluorophenyl trifluoromethyl ketone; 2,2,2-Trifluoro-1-(3,5-dichloro-4-fluorophenyl)ethanone; 1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethan-1-one; 3,5-Dichloro-α,α,α-trifluoro-4-fluoroacetophenone; (3,5-Dichloro-4-fluorophenyl)(trifluoromethyl)methanone; Trifluoro(3,5-dichloro-4-fluorophenyl)methanone; CAS 1190865-44-1
EINECS	Contact for details

Quality Control

Our 1-(3,5-Dichloro-4-Fluorophenyl)-2,2,2-Trifluoroethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.