Description

2,3,4-Trifluoroiodobenzene is a high-value, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique combination of fluorine and iodine substituents makes it a critical reagent for introducing fluorinated aryl groups via cross-coupling reactions, enabling the development of novel compounds with tailored properties. This intermediate is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs) and drug candidates via Suzuki, Stille, and other cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the trifluorophenyl moiety enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic materials, improving charge transport and thermal stability in display technologies.
• Polymer & Specialty Chemistry: Employed to create fluorinated monomers and polymers, imparting desirable properties like chemical resistance, low surface energy, and thermal endurance.
• Radiolabeling Precursor: The iodine atom provides a potential site for radioiodination, useful in developing diagnostic imaging agents and tracers for research.
• General Organic Synthesis: A versatile reagent for nucleophilic aromatic substitution and metal-halogen exchange reactions to construct complex, fluorinated molecular architectures.

Basic Information

Item	Detail
Product Name	2,3,4-Trifluoroiodobenzene
CAS No.	1190385-23-9
Molecular Formula	C6H2F3I
Molecular Weight	261.98 g/mol
Synonyms	1-Iodo-2,3,4-trifluorobenzene; 2,3,4-Trifluoro-1-iodobenzene; Benzene, 1-iodo-2,3,4-trifluoro-; Iodotrifluorobenzene (mixed isomer reference); 2,3,4-Trifluorophenyl iodide
EINECS	Contact for details

Quality Control

Every batch of 2,3,4-Trifluoroiodobenzene is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.