Description

2-[4-(4-Methoxy-Phenylethynyl)-Phenyl]-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. This compound matters for its role as a key intermediate in cross-coupling reactions, enabling the efficient synthesis of complex organic molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of advanced materials, agrochemicals, and active pharmaceutical ingredients (APIs).

Application

This versatile boronic ester is a cornerstone reagent in advanced organic synthesis, with key applications including:

• Suzuki-Miyaura Cross-Coupling Reactions: As a pivotal coupling partner for constructing biaryl and conjugated systems essential in pharmaceuticals and organic electronics.
• Pharmaceutical Intermediate Synthesis: Serving as a key building block in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Material Science Research: Used in the development of organic light-emitting diodes (OLEDs), liquid crystals, and other advanced functional materials requiring precise molecular architecture.
• Agrochemical Development: Acting as an intermediate in the synthesis of new generation herbicides, fungicides, and plant growth regulators.
• Chemical Biology & Probe Development: Utilized for labeling and modifying biomolecules or creating molecular probes for diagnostic applications.

Basic Information

Product Name	2-[4-(4-Methoxy-Phenylethynyl)-Phenyl]-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane
CAS No.	1190376-24-9
Molecular Formula	C21H23BO3
Molecular Weight	334.22 g/mol
Synonyms	4-(4-Methoxyphenylethynyl)phenylboronic acid pinacol ester; (4-((4-Methoxyphenyl)ethynyl)phenyl)boronic acid pinacol ester; 2-[4-[2-(4-Methoxyphenyl)ethynyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Methoxy-phenylethynyl-phenylboronic acid pinacol ester; Pinacol [4-(4-methoxyphenylethynyl)phenyl]boronate
EINECS	Contact for details

Quality Control

Our 2-[4-(4-Methoxy-Phenylethynyl)-Phenyl]-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency suitable for demanding research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.