Description

6-Fluoro-4-Azaindole-3-Carboxaldehyde is a high-purity, advanced pharmaceutical intermediate with the CAS number 1190316-09-6. This compound is a critical building block in modern medicinal chemistry, valued for its unique azaindole scaffold and reactive aldehyde functionality. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and development of novel small-molecule therapeutics, particularly kinase inhibitors and other targeted agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new bioactive molecules.
• Chemical Biology Probes: Serves as a starting material for creating labeled compounds or probes to study biological pathways and target engagement.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for exploring novel heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	6-Fluoro-4-Azaindole-3-Carboxaldehyde
CAS No.	1190316-09-6
Molecular Formula	C8H5FN2O
Molecular Weight	164.14 g/mol
Synonyms	6-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehyde; 6-Fluoro-4-azaindole-3-carbaldehyde; 3-Formyl-6-fluoro-4-azaindole; 6-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde; 6-Fluoro-4-aza-indole-3-carboxaldehyde; 6-Fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)methanone (tautomer); 6-Fluoro-7-azaindole-3-carboxaldehyde (common alternate numbering)
EINECS	Contact for details

Quality Control

Our 6-Fluoro-4-Azaindole-3-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (by NMR and MS), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 5.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.