Description

1,6-Bis[3-(Trifluoromethyl)-3H-Diazirin-3-Yl]-3,8-Dimethoxy-Dibenzene is a specialized, high-purity chemical building block featuring a unique diazirine-based photoaffinity labeling core. This compound is critical for advanced research and development in photochemistry and life sciences, enabling precise molecular cross-linking and target identification studies. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and specialty chemical manufacturers developing next-generation probes and materials. This product is discontinued, indicating its specialized nature and the importance of securing remaining inventory for critical projects.

Application

• Photoaffinity Labeling Probes: Acts as a core photoreactive moiety in the synthesis of probes for identifying and studying biological targets, such as proteins and enzymes.
• Chemical Biology Research: Used in the development of tools for mapping protein-protein interactions and ligand binding sites through covalent cross-linking upon UV light activation.
• Proteomics and Drug Discovery: Integral to creating reagents for activity-based protein profiling (ABPP) and identifying off-target effects of drug candidates.
• Material Science Cross-linking: Employed in the surface functionalization and cross-linking of polymers or nanomaterials to create advanced smart materials with light-responsive properties.
• Synthesis of Diazirine-Containing Analogs: Serves as a key intermediate for synthesizing more complex molecules containing the versatile 3-(trifluoromethyl)-3H-diazirin-3-yl group.

Basic Information

Product Name	1,6-Bis[3-(Trifluoromethyl)-3H-Diazirin-3-Yl]-3,8-Dimethoxy-Dibenzene (Discontinued)
CAS No.	1189941-02-3
Molecular Formula	C18H10F6N4O2
Molecular Weight	428.29 g/mol
Synonyms	1,6-Bis(3-(trifluoromethyl)diazirin-3-yl)-3,8-dimethoxydibenzene; 3,8-Dimethoxy-1,6-bis[3-(trifluoromethyl)-3H-diazirin-3-yl]dibenzene; 1,6-Bis(3-trifluoromethyl-3H-diazirin-3-yl)-3,8-dimethoxybenzene; Diazirine Cross-linker; Photoaffinity Labeling Reagent; Bis(trifluoromethyldiazirine) Derivative; Aromatic Diazirine Compound
EINECS	Contact for details

Quality Control

As a discontinued, high-value research chemical, each batch of this product was manufactured under strict quality protocols to ensure identity and purity for sensitive applications. Quality is verified through analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and lot-specific data is provided with every shipment to support your research integrity and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere to maximize stability of the light- and potentially moisture-sensitive diazirine functional groups. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.