Description

4-Ethoxyphenylglyoxal Hydrate is a versatile and reactive α-dicarbonyl compound, serving as a key synthetic intermediate in advanced organic synthesis. Its value lies in its ability to introduce the glyoxal functional group into aromatic systems, enabling the construction of complex heterocycles and fine chemicals. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those containing heterocyclic scaffolds like imidazoles, quinoxalines, and fused ring systems.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators that require specific aromatic-glyoxal motifs.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and advanced organic materials where the ethoxyphenyl group confers specific electronic or solubility properties.
• Chemical Research & Development: Serves as a standard reagent in methodological studies for new C-C and C-N bond-forming reactions involving α-dicarbonyl compounds.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized chelating ligands used in coordination chemistry and catalysis.

Basic Information

Product Name	4-Ethoxyphenylglyoxal Hydrate
CAS No.	1189873-72-0
Molecular Formula	C10H10O4 • xH2O
Molecular Weight	194.18 g/mol (Anhydrous basis)
Synonyms	2-Oxo-2-(4-ethoxyphenyl)acetaldehyde Hydrate; (4-Ethoxyphenyl)glyoxal Hydrate; 4-Ethoxybenzoylformaldehyde Hydrate; p-Ethoxyphenylglyoxal Hydrate; 1-(4-Ethoxyphenyl)-1,2-ethanedione Hydrate; Glyoxal, (4-ethoxyphenyl)-, Hydrate; 4-Ethoxy-α-oxobenzeneacetaldehyde Hydrate
EINECS	Contact for details

Quality Control

Our 4-Ethoxyphenylglyoxal Hydrate is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all relevant specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 3.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.