Description

2-Methylindazole-5-Boronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its value lies in enabling the precise and efficient construction of complex heterocyclic molecules, which are critical scaffolds in advanced material and pharmaceutical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing indazole motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with complex heterocyclic structures.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biochemical assays and diagnostic research.
• Academic & Contract Research: A valuable reagent for methodology development and exploring new catalytic processes in university and CRO laboratories.
• Scale-up & Process Chemistry: Suitable for optimization and scaling from milligram to kilogram quantities for pilot plant and commercial production pathways.

Basic Information

Product Name	2-Methylindazole-5-Boronic Acid Pinacol Ester
CAS No.	1189746-27-7
Molecular Formula	C₁₄H₁₉BN₂O₂
Molecular Weight	258.13 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methyl-1H-indazole; 2-Methyl-1H-indazole-5-boronic acid pinacol ester; 2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 2-Methyl-1H-indazol-5-ylboronic acid pinacol ester; 2-Methylindazole-5-boronic acid, pinacol ester; 1189746-27-7; BRN 19105738
EINECS	Contact for details

Quality Control

Every batch of 2-Methylindazole-5-Boronic Acid Pinacol Ester is produced and tested under strict quality management protocols to ensure consistency and reliability for critical synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.